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Ulcerative Colitis Low Undetected Colorectal Cancer Risk

, Preoperative dysplasia among patients with ulcerative colitis undergoing colectomy was linked to a low risk for undetected synchronous colorectal cancer in a study presented at the American Society of Colon and Rectal Surgeons Annual Meeting in Phoenix.

Researchers evaluated the medical records of 2,130 patients with ulcerative colitis (UC) who underwent proctocolectomy, restorative proctocolectomy or total colectomy between August 1993 and July 2012. Preoperative colorectal dysplasia was detected in 15% of the cohort.

The literature to date varies widely with regard to the importance of dysplasia as a marker for colorectal cancer (CRC) at the time of colectomy, the researchers wrote. This study aims to accurately characterize the extent to which the preoperative detection of dysplasia is associated with undetected CRC in patients with UC.

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